Provigil (modafinil) is a medication that promotes wakefulness. It is thought to work by altering the natural chemicals (neurotransmitters) in the brain.
Provigil is used to treat excessive sleepiness caused by sleep apnea, narcolepsy, or shift work sleep disorder.

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Take Provigil exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Provigil is usually given for 12 weeks or less. Follow the directions on your prescription label.

Side Effect

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using Provigil and call your doctor at once if you have any of these serious side effects:
•fever, sore throat, headache, and vomiting with a severe blistering, peeling, and red skin rash;
•bruising, severe tingling, numbness, pain, muscle weakness;
•easy bruising or bleeding;
•white patches or sores inside your mouth or on your lips;
•hallucinations, unusual thoughts or behavior;
•depression, anxiety, aggression; or
•chest pain, uneven heart beats.

Less serious Provigil side effects may include:
•headache, dizziness;
•feeling nervous or agitated;
•nausea, diarrhea;
•trouble sleeping (insomnia); or
•dry mouth.


You should not use Provigil if you are allergic to modafinil or armodafinil (Nuvigil).
To make sure you can safely take Provigil, tell your doctor if you have any of these other conditions:
•angina (chest pain);
•cirrhosis or other liver problem;
•kidney disease;
•a heart muscle or valve disorder such as mitral valve prolapse;
•a history of drug addiction;
•if you take blood pressure medications; or
•if you have recently had a heart attack.